StatLogic Sports Week 10 NFL Fantasy & DFS Game Day Guide

For full-season fantasy football managers and DFS players, Week 10 of the 2025 National Football League season just isn't easy.

This week brings us more byes, with the Bengals, Cowboys, Chiefs and Titans sitting this one out, along with the usual array of November injuries. On top of that, we've got the early morning Sunday game in Germany and it seems like this week the Gales of November finally will be swirling.

Yep., Throw some bad weather into the mix for good measure, and what we have is a week of extremely difficult - if not impossible - decisions.

Swift or Monangai? Stevenson, Henderson or Jennings? Tracy of Singletary? Bam or Demercado? Walker or Charbonnet? Gibbs or Monty? Puka or Davante? Jones or Mason? Moore or Odunze?

We could go on for many more paragraphs listing the challenging decisions that face fantasy football enthusiasts this week, and we could spend hundreds of words complaining about the situation, but really isn't this why we play? Isn't this what makes it fun.?

No doubt there is a lot of luck involved in fantasy football and DFS, but these are the weeks that can separate the pretenders from the contenders. This is where we can prove ourselves. The full-season managers who have put in the work to build a deep roster at least have options who can help them win games instead of having to just put throwaway bottom-of-the-depth-chart players in their lineups and praying for lightning to strike.

Options are good, but they also force us to make difficult decisions. And from this point on, the decisions are only going to get more difficult as the wear and tear of the grueling NFL season takes its toll on more players, injuries continue to mount and the weather continues to deteriorate.

The key to a successful Week 10 is to simplify and do all we can to make the decisions we face as black and white as possible. For the most part, we're going to go with the chalk and guaranteed higher-floor players as much as possible. Don't bench your clear No. 1 receiver or running back because of a tough matchup. Even if they have a week that isn't up to their standards, the 7-10 points they might get you likely will make a difference.

Many managers these days look at snap counts when making tough lineup decisions, but this week let's challenger ourselves to look more at touches and production - because most of our opponents probably are looking for snap counts.

It's great that TreyVeon Henderson got more playing time than Terrell Jennings last week, but who got the ball more and who was used in scoring situations? Bam Knight and Emari Demercado present a similar managerial conundrum.

The player who receives the higher percentage of touches per snap and is the most productive is the way to go. If playing time is skewed but touches are equal, simply go with the player who has been most productive - but don't let one outlier week or a couple of random touchdowns in a game impact the final decision. Study the dynamic over time and look for matchups and situations that are similar to what their teams face this week to determine which player is likely to be most productive.

Volume is king. Touches over TDs. Production over snaps.

This is how most of us should be approaching Week 10 in both full-season and DFS formats. Of course, anyone playing large DFS tournaments with high payouts should be looking for some potentially explosive players who may not be highly owned, while full-season managers who are desperate for a win or facing a high-scoring opponent might want to include some of the riskier and higher-upside players in their lineups instead of the safer, higher-floor players.

As for the weather, on a normal day the Bears-Giants game would be one that many fantasy footballers would look to on many levels. Both quarterbacks have solid matchups and can use their legs; they normally would be great DFS plays at value prices and worth considering as at least streamers if not to full-time starters in full-season formats.

Although they present one of those difficult decisions, the Bears running backs both would be worthy of consideration as would their top three receivers. New York WR Wan'Dale Robinson is on almost every pundit's list of players to target or start this week, The names Williams, Dart, Swift, Monangai, Odunze, Moore and Robinson are plastered all over this week's fantasy football analyses.

That was before the reality of harsh weather was considered, however. Winds with consistent gusts of 20 mph are expected throughout that game today, and a mix of rain and snow is possible. Dart and Williams are not the most accurate passers, and the wind might present a problem for them and their receivers. Both players are athletic and mobile, but Dart is much more willing to run and comfortable with the idea of taking on defenders to get a few extra yards. Chicago's run game has been among the best in the league no matter who is carrying the ball the last four weeks.

Normally we would value Williams over Dart in this matchup because of the volume of passes he generally throws, Chicago's depth at the receiver position and his ability to run when plays break down. Dart always is worth considering as a leverage play if his salary is lower because of his legs. If he saves us money and we are confident he will get to a certain floor at a price that allows us to pay up for a top-tier guy at another position, he is usually worth playing in at least one lineup.

Most people who play DFS are more casual about it; they enjoy having something to root for and a shot at winning a few bucks. Many will not even know about the impending weather and are likely to plug Williams into their lineups with one of the Chicago receivers without hesitation based on the matchups alone. But the serious and successful DFS players might pivot to Dart instead while also adding whichever Chicago back they prefer along with a player like Robinson. Even in bad weather, Robinson is getting most of New York's targets and is a solid floor play at a very reasonable price. We'd consider using him in multiple lineups.

Some of the best and safest matchups this week involve the most expensive top-tier players, and they often provide the best combination of ceiling and floor. So, the goal should be to get as many of them in our DFS lineups as possible while finding the safest lower-priced higher-floor players to surround them with.

Any of those players on full-season rosters should be in the lineup, too, regardless of their matchup. From there, it's just a matter of putting the puzzle pieces in place with the players who are most likely to give us the best chance of being successful. Leave the guessing or riskier plays to others unless it's a must-win situation against a high-powered team.

Good luck!

Below are some lineup suggestions for this week based on games in the FanDuel Sunday main slate:

Pay-up Quarterbacks

1. Josh Allen

2. Lamar Jackson

Since these guys are at the top of the salary chart, it's worth considering a stack that incudes them with more affordable teammates such as Josh Palmer, Rashod Bateman, Mark Andrews or Isaiah Likley.

Volume Matchup Quarterbacks

1. Jared Goff

2. Matthew Stafford

3. Baker Mayfield

Goff has a no-brainer matchup vs. a Washington team that can't cover your mom. Stafford has been lights out and is surrounded. by weapons playing against a depleted 49'ers defense. They are in a better situation than Mayfield given Tampa Bay's injury situation, but we expect him to bounce back from a rough performance coming out of a bye that gave him two weeks to ponder his most-recent outing.

Dual Threat Quarterbacks

1. Jaxson Dart

2. Drake Maye

Maye had been amazing this year but has started to get hit quite a bit, and the Buccaneers are likely to blitz him all day. He's a solid floor play because of his legs and does have higher upside than Dart. Todd Bowles has a way of making things tough for a young QB, though, and Dart's price tag is $500 cheaper, so he's our top choice here.

Bargain Leverage Quarterback

1. Marcus Mariota

Washington just plugs him into the Daniels offense and he seems to produce 18-23 points every time he starts at a price that allows us to stack the rest of the lineup.

Pay-up Stud Running Back

1. Christian McCaffrey

High volume, high floor, high ceiling.

Target Volume Pay-up Running Backs

1. James Cook

2. De'Von Achane

3. Rico Dowdle

4. Jahmyr Gibbs

One of these guys - or CMC - should be in every lineup. Beware of Gibbs, though. A blowout might lead to more carries for Monty, who we would consider strongly as a pivot at a much better price.

Contrarian Volume Running Backs

1. Derrick Henry

2. Kyren Williams

Volume and high floors for both. And we know Henry's potential upside, while Williams gets all the goal-line work for the Rams. Very solid picks this week, especially in larger tournaments.

Value Volume RB1

1. Quinshon Judkins

Decisions, Decisions RB Edition

1. Swift or Monangai

2. Henderson or Jennings

3. Walker or Charbonnet

Playing either Swift or Monangai is fine, and we'd try to get one of them in every lineup. Monitor the injury info, and if Swift doesn't play, Monangia must be rostered on multiple teams.

As for the Patriots, we prefer Jennings as a low-priced leverage play, but based on how a lineup is structured, Henderson is a fine choice at $5,900 Walker and Charbonnet have pretty good matchups, but both are priced a little too high for the risk involved. In this case, we'd take Charbonnet based on his ability to hit the occasional home run and goal-line opportunities.

Safe High-floor RB2

1. Travis Etienne

He's a bit of a contrarian play, which is never bad, and he gets plenty of touches. At j$6,900, we prefer him to any of the backs that involve decisions except the Chicago duo.

Bargain Leverage RB2/Flex Options

1. Chris Rodriguez

2. Emari Demercado

Rogriguez was named one of Washington's captains this week. He looked great last wee coming off the bench, and is worth a shot at RB2 with his $5,600 salary if he's paired with one of the stud RBs.

Pay-up Top-tier Wide Receivers & Pivots

Get one or two of these guys into every lineup. And if they don't fit, go with one of their pivots, who are also listed below with them.

1. Amon-Ra St. Brown - Jameson Williams

2. Puka Nacua - Davante Adams

3. Jaxon Smith-Njigba - Rashid Shaheed or Cooper Kupp if he plays

4. Justin Jefferson - Jordan Addison

Value Volume Wide Receivers

1. Wan'Dale Robinson

2. Emeka Egbuka

3. Jaylen Waddle

4. Zay Flowers

5. Marvin Harrison

6. Deebo Samuel

7. Rome Odunze/DJ Moore

Odunze or Moore would top this list if not for the weather.

Value Core Wide Receiver

1. Wan'Dale Robinson

At $6,000 and sure to get a ton of targets, he's a no-brainer.

High-value WR2 or Flex

1. Khalil Shakir

2. Stefon Diggs

Leverage Bargain WR3/Flex

1. DeMario Douglas

2. Parker Washington

3. Darius Slayton

4. Tez Johnson

5. Malik Washington

6. Olamide Zaccheus

7. Cedric Tillman

8. Rashod Bateman

9. Kendrick Bourne

10. Jaylin Lane

Core Value Tight End

1. Cade Otton

At $5,400 and probably as Mayfield's No. 2 option, we will have him in most - if not all - lineups.

Pay-up Tight End

1. Trey McBride

Volume Tight Ends

1. Sam LaPorta

2. Dalton Kincaid

3. George Kittle

Leverage Bargain Tight Ends

1. Greg Dulcic

2. Isaiah Likely

Dulcic's talent has never been questioned, and he's in possibly the league's most tight-end friendly offense (see Jonnu Smith and Darren Waller). He's a huge sleeper who caught all five targets in Week 9. If he does that again at $4,000, he will make us money.